D6003
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D6003
Fluka
Digoxin
≥95.0% (HPLC)
| Synonym: | 12β-Hydroxydigitoxin |
| CAS Number: | 20830-75-5 |
| Linear Formula: | C41H64O14 |
| Molecular Weight: | 780.94 |
| Beilstein Registry Number: | 77011 |
| EC Number: | 244-068-1 |
| MDL number: | MFCD00003674 |
| PubChem Substance ID: | 24893992 |
Description
| Biochem/physiol Actions | A cardiac glycoside, substrate for Pgp, upregulates Pgp expression and down regulates SXR (Steroid Xenobiotic Receptor). |
Properties
| assay | ≥95.0% (HPLC) |
| Gene Information | human ... ABCB1(5243), CYP3A4(1576) |
| rat ... Atp1a1(24211) | |
| mouse ... Abcb1a(18671), Abcb1b(18669) |
Safety
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 22-36/37/39-45 |
| RIDADR | UN3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | IH6125000 |
References
| reference | Takara, K., et al. Biochem. Biophys. Res. Commun. 306, 116-120, (2003) |
| Merck | Merck 13,3189 |
| Beilstein | Beil. 18,V,4,381 |
